Skin Study Center

The Skin Study Center in the Department of Dermatology is a translational research facility dedicated toward advancing our understanding about various skin diseases and skin health. The unit serves as a facility for human volunteers who are participating in basic or clinical research studies. Located in 512 Wearn within University Hospitals, the Skin Study Center plays a pivotal role in various investigative research projects pertaining to immunology, photobiology, and various skin and hair diseases (e.g. psoriasis, atopic dermatitis, contact dermatitis, alopecia areata, skin cancers). The facility houses a 1000-Watt solar simulator, skin ultrasound machine, transepidermal water loss unit (TEWL), chromometer, digital cameras, other UV sources and UV meters, motorized AESCULAP keratome device for horizontal skin biopsies, and micrometer for measurement of skin thickness.

As a translational core facility affiliated with both Case Western Reserve University and University Hospitals of Cleveland, we are unique in that we provide support and resources for our own team of nationally renowned researchers in addition to other departmental and industry-sponsored clinical research studies. We work closely with the NIH-funded General Clinical Research Center and National Cancer Institute-designated Case Comprehensive Cancer Center/Ireland Cancer Center.

Currently, we are conducting various studies focused on psoriasis, atopic dermatitis, skin cancers, lymphoma, and tests on new and future sun protection creams and products.

 

Current Studies
  1. One of our interests centers on understanding more about the cellular causes of psoriasis. Many therapies and treatments are often ineffective, risky, or inconvenient. We hope to improve treatments for psoriasis by understanding more about psoriatic cells, cellular signaling pathways, and how UV light creates changes in lesions. In doing so, we need volunteers who have psoriasis that have not used any creams, topical steroids, or light therapy in the past 2 weeks. For the study, we need individuals to donate blood and skin samples. Volunteers will be paid for their time and effort.
     
  2. Normal, healthy individuals are needed for a study looking to develop a non-invasive screening system that can be used to evaluate new sun protection products and sunscreens. Some parts of the study may require punch biopsies. Recruitment is ongoing for this large-scale study. Participants will be compensated for their time and effort.
     
  3. Individuals with Rosacea are invited to participate in a study that is evaluating the effectiveness of a green tea cream. The eight week study requires twice daily applications of the topical cream and 4 bi-weekly visits to the Skin Study Center. You should not be on any topical or oral medications to participate in the study. Participants will be compensated for their time and effort.
     


(216) 844-SKIN (7546) for more information.


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Downtown Cleveland